Answers are grounded in this paper and cite their sources.
Demonstrates that magnetite nanoparticle injections alter electrical impedance in porcine heart tissue, suggesting potential utility as a contrast agent for tissue characterization.
Objectives. Electrical impedance spectroscopy (EIS) is a harmless non-invasive technique that allows to measure and monitor different physiological parameters. One of the problems with establishing new procedures based on EIS is difficulty to distinguish between tissue types. For that reason, our research group have decided to assess a possibility to use nanomagnetite as a contrast medium in EIS procedures. In this work we present characterization the electrical properties of a porcine heart tissue by EIS using a magnetite particles suspension as contrast medium. Methodology. SP-150 from BioLogic Science Instruments was used as EIS equipment. Porcine heart tissue was used as biological tissue. Nanomagnetite particles were synthetized by coprecipitation and combustion methods and named NM1 and NM2, respectively. EIS device was connected at each ventricle through four hypodermic needles (38mm). Left and right ventricle was injected with NM1 and NM2 particles, respectively. Impedance measurements were acquired for each ventricle before and after the injection. Contribution. Both samples of magnetite nanoparticles were able to change electrical properties of heart tissue. Studies in vivo must be performed in order to confirm the conclusion.
No takes yet. Share an insight, caveat, or question.
Solis-Rojas et al. (2019) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: