Sites of Vagal Action in Adrenaline-Induced Cardiac Arrhythmias

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Population

Barbiturate-anesthetized dogs

Design

Preclinical

Authors

Discussion

Hypothesis-generating for vagal AV nodal effects on ventricular escape; human validation required before clinical consideration.

Population

Barbiturate-anesthetized dogs

Intervention

Adrenaline administration

Outcome

Induction of ventricular arrhythmia and AV nodal blocksurrogate

Vagal action on AV nodal conduction facilitates the emergence of ventricular pacemakers during adrenaline-induced arrhythmias in canine models.

Peter E. Dresel (1962) studied this question.

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