Why the study?
Does total [51Cr]EDTA plasma clearance provide better precision and reproducibility for GFR determination compared to 24-hr endogenous creatinine clearance and estimated creatinine clearance in adult patients?
Population
51 adult patients
Comparison
Total [51Cr]EDTA plasma clearance (E) vs 24-hr endogenous creatinine clearance and…
Design
Cross-sectional
Authors
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Supports [51Cr]EDTA clearance for precise GFR assessment in eGFR ≥30 ml/min; hypothesis-generating and should not yet change practice.
Does total [51Cr]EDTA plasma clearance provide better precision and reproducibility for GFR determination compared to 24-hr endogenous creatinine clearance and estimated creatinine clearance in adult patients?
Total [51Cr]EDTA plasma clearance offers superior precision and reproducibility compared to 24-hour and estimated creatinine clearance for routine GFR assessment.
Brøchner‐Mortensen et al. (1976) studied this question.
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