Why the study?
Does cumulative duration of bispectral index (BIS) < 45 or cumulative anesthetic dose affect intermediate-term mortality in patients undergoing noncardiac surgery?
Population
1,473 patients undergoing noncardiac surgery at a single center in St. Louis, Missouri.
Comparison
Bispectral index monitoring and cumulative… vs Unmonitored patients or different durations/doses.
Design
Cohort
Follow-up
3.2 ± 1.1 years
Authors
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No mortality link with BIS <45 duration in noncardiac surgery; leaves open whether depth titration affects survival.
Does cumulative duration of bispectral index (BIS) < 45 or cumulative anesthetic dose affect intermediate-term mortality in patients undergoing noncardiac surgery?
Limiting depth of anesthesia by titration to a specific BIS threshold or limiting end-tidal volatile agent concentrations does not appear to decrease postoperative mortality in noncardiac surgery.
Kertai et al. (2011) studied this question.
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