Pseudomonas Chemotaxis, Motility and Host-Pathogen Interactions

Infection with the fluorescent pathogen Pseudomonas aeruginosa leads to gastrointestinal infections, dermatitis, bacteremia and a variety of systemic infections. Thus, within a very complex chemosensory system this bacterium has requires an adaptive strategy to escape to the immune system. It chemosensory system has attracted a significant interest because of the very complex molecular diversity of this one (> 20 chemotaxis (che) genes). With this diversified chemotaxis system, this bacteria moves from cell to cell by a twitching motility and respond in a behavioral manner. For this, it can be viewed as an important prelude to infections and serious clinical challenge.