Why the study?
Does treatment-resistant or insufficiently treated depression increase all-cause mortality in patients with major depressive disorder following myocardial infarction?
Population
4037 patients with major depressive disorder who had had a myocardial infarction
Comparison
Insufficiently treated depression or… vs Treated depression
Design
Cohort
Follow-up
mean 39 months
Authors
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Inadequate post-MI depression treatment was associated with higher mortality; leaves open whether optimization improves survival.
Does treatment-resistant or insufficiently treated depression increase all-cause mortality in patients with major depressive disorder following myocardial infarction?
In patients with major depressive disorder following myocardial infarction, insufficient treatment or treatment resistance is associated with significantly higher all-cause mortality compared to adequate treatment.
Scherrer et al. (2012) studied this question.
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