Why the study?
Does occupational exposure to lead, zinc, and copper affect autonomic nervous system function and peripheral nerve conduction in male workers?
Population
32 male subjects (16 workers exposed to lead, zinc, copper, and tin, and 16 unexposed control subjects)
Comparison
Occupational exposure to lead, zinc, copper, and… vs Unexposed control subjects
Design
Cross-sectional
Authors
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Should not yet alter occupational exposure standards; extends observational evidence on metal neurotoxicity but requires prospective validation.
Does occupational exposure to lead, zinc, and copper affect autonomic nervous system function and peripheral nerve conduction in male workers?
Subclinical autonomic neurotoxicity, specifically in the parasympathetic component, and peripheral nerve dysfunction occur in workers exposed to lead, though zinc may have an antagonistic effect.
Murata et al. (1991) studied this question.
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