Why the study?
Does Qiliqiangxin attenuate adverse cardiac remodeling after acute myocardial infarction in mice?
Population
Mice with acute myocardial infarction induced by ligation of the left anterior descending coronary artery.
Comparison
Qiliqiangxin administered in the initial 3 days… vs Control animals with AMI.
Design
Preclinical
Follow-up
3 weeks
Authors
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Should not yet alter post-MI care; extends preclinical evidence for QLQX via PPARγ in mice.
Does Qiliqiangxin attenuate adverse cardiac remodeling after acute myocardial infarction in mice?
Qiliqiangxin mitigates adverse cardiac remodeling and preserves cardiac function after acute myocardial infarction in mice via a PPARγ-dependent mechanism.
Tao et al. (2015) studied this question.
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