Population
Glycerinated fibres from rabbit psoas muscle
Comparison
Aluminofluoride and orthovanadate vs Uninhibited state / recovery from inhibition
Design
Preclinical
Authors
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Does not inform clinical decisions; leaves open whether early cross-bridge states modulate cardiac performance in vivo.
Inorganic phosphate analogues AlFx and Vi inhibit force more than stiffness or unloaded shortening velocity in rabbit psoas muscle fibers, suggesting they bind to cross-bridges early in the cycle.
Chase et al. (1993) studied this question.
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