We report a successful renal transplant in a highly sensitised paediatric recipient following removal of HLA-specific antibodies by extracorporeal immunoadsorp-tion. The immediate pretransplant cytotoxic titre against the donor was greater than 1:512; this was reduced to negativity by two immunoad-sorption sessions prior to transplant surgery. We also describe the presence of unexpected non-HLA-spe-cific antibody activities in this im-munoadsorbed patient.
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Bevan et al. (1996) studied this question.
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