Why the study?
Does a single dose of propranolol or metoprolol affect performance during acute stress in patients with untreated essential hypertension?
Does a single dose of propranolol or metoprolol affect performance during acute stress in patients with untreated essential hypertension?
A single dose of propranolol or metoprolol does not significantly alter performance during acute stress (simulated driving) in patients with untreated essential hypertension.
Answers are grounded in this paper and cite their sources.
Single-dose beta-blockers may not impair performance under acute stress in untreated hypertension; leaves open effects on chronic BP reactivity.
A standardized method of objectively measuring performance during simulated car driving is described. 2. The effect of a single dose of propranolol and metoprolol were compared with placebo in two groups of patients with untreated essential hypertension. 3. Performance was similar after beta-adrenoreceptor-blocking agents or placebo. 4. Blood pressure response to stress persisted after administration of the blocking agents.
No takes yet. Share an insight, caveat, or question.
Dunn et al. (1979) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: