Why the study?
Does tannic acid reduce pressure overload-induced cardiac hypertrophy in male Wistar rats?
Population
Male Wistar rats with pressure overload-induced cardiac hypertrophy induced by abdominal aortic banding (AAB)
Comparison
Tannic acid (20 and 40 mg/kg) or captopril vs Sham-operated rats and untreated AAB rats
Design
Preclinical
Authors
Loading...
Hypothesis-generating in rodent hypertrophy models; human translation and clinical relevance remain untested.
Does tannic acid reduce pressure overload-induced cardiac hypertrophy in male Wistar rats?
Tannic acid attenuates pressure overload-induced cardiac hypertrophy in rats by inhibiting oxidative stress, inflammation, fibrosis, and apoptosis.
Chu et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: