Why the study?
Does short-term insulin treatment improve myocardial cell dysfunction in diabetes mellitus?
Population
Patients and experimental models with diabetes mellitus and diabetic cardiopathy
Design
Review
Authors
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Short-term insulin may reverse diabetic myocardial calcium defects; hypothesis-generating and should not yet change practice.
Does short-term insulin treatment improve myocardial cell dysfunction in diabetes mellitus?
This review highlights that myocardial cell dysfunction in diabetes, driven by calcium homeostasis and receptor signaling abnormalities, may be reversible with short-term insulin therapy.
Ole Gøtzsche (1986) studied this question.
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