Why the study?
Does microembolisation-induced ischaemia alter the gene expression of IGFs and interleukins in a porcine heart model?
Does microembolisation-induced ischaemia alter the gene expression of IGFs and interleukins in a porcine heart model?
In a porcine model of microembolisation, increased IGF-I mRNA expression by infiltrating monocytes suggests its involvement in inflammation-linked angiogenic processes.
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Hypothesis-generating for IGF-I in post-ischemic cardiac inflammation; leaves open translation to human angiogenesis or therapy.
Kluge et al. (1995) studied this question.
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