Population
Cats anaesthetized with a mixture of chloralose and urethane
Comparison
Stimulation of pulmonary C fibres by right… vs Control responses in the absence of laryngeal…
Design
Preclinical
Authors
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Highlights mechanistic distinction from carotid chemoreflexes in animals; leaves human translation and clinical relevance open.
This preclinical study demonstrates that cardiovascular responses to pulmonary C fibre stimulation are mediated by reduced sympathetic vasoconstrictor activity and are not modulated by respiration, unlike carotid chemoreceptor reflexes.
Daly et al. (1988) studied this question.
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