Why the study?
Does the severity of surgical trauma affect plasma levels of cyclic AMP, glucose, and cortisol?
Population
16 patients undergoing surgery (6 major surgery/hysterectomy, 10 minor surgery/tympanoplasty)
Comparison
Major surgery (hysterectomy) vs Minor surgery (tympanoplasty)
Design
Cohort
Follow-up
before, during and after surgery
Authors
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May inform perioperative stress monitoring by procedure scale; leaves open validation as prognostic markers in prospective cohorts.
Does the severity of surgical trauma affect plasma levels of cyclic AMP, glucose, and cortisol?
The increase in plasma cyclic AMP during operative procedures is related to the severity of the surgical trauma.
Madsen et al. (1976) studied this question.
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