Why the study?
Does surgical trauma affect plasma concentrations of cyclic AMP and cortisol in general surgical patients?
Population
7 general surgical patients
Comparison
Surgical trauma (operation) vs Preoperative levels
Design
Case_series
Follow-up
up to 48 hours postoperatively
Authors
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May signal intraoperative stress without altering practice; leaves open cAMP-ACTH mediation in larger cohorts.
Does surgical trauma affect plasma concentrations of cyclic AMP and cortisol in general surgical patients?
Surgical trauma induces a significant rise in plasma cyclic AMP during the operation, which may mediate subsequent ACTH release.
Gill et al. (1975) studied this question.
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