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August 1, 1962Journal of Clinical InvestigationOpen Access

Acth Levels in Plasma in Preoperative and Surgically Stressed Patients*

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Why the study?

Does surgical stress increase ACTH levels in plasma in patients?

Population

Preoperative and surgically stressed patients

Comparison

Surgical stress vs Preoperative state

Design

Other

Authors

CCCollin E. CooperUniversity of Southern CaliforniaDNDon H. NelsonUnited States Army

Discussion

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Implication

Does not yet alter perioperative ACTH assessment; leaves open direct surgical stress effects pending controlled human validation.

Structured PICO

Does surgical stress increase ACTH levels in plasma in patients?

P
Population
Preoperative and surgically stressed patients
I
Intervention
Surgical stress
C
Comparator
Preoperative state
O
Outcome
ACTH levels in plasmasurrogate

This study investigates whether surgical stress directly drives ACTH release in humans.

Cite This Study

Cooper et al. (1962) studied this question.

synapsesocial.com/papers/6a89553ec89a2b4713ec64e9https://doi.org/10.1172/jci104618
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CONJUGATED 17-HYDROXYCORTICOSTEROIDS IN PLASMA: MEASUREMENT AND SIGNIFICANCE IN RELATION TO SURGICAL TRAUMA*1961 · 9 citations
  2. 2Statistical Tables for Biological, Agricultural and Medical Research.1944 · 3,009 citations
  3. 3METABOLISM OF FREE AND CONJUGATED 17-HYDROXYCORTICOSTEROIDS IN SUBJECTS WITH THYROID DISEASE*1958 · 89 citations