Why the study?
Does high salt intake induce cardiac hypertrophy and alter the cardiac renin-angiotensin system independently of hypertension in Dahl salt-sensitive rats?
Does high salt intake induce cardiac hypertrophy and alter the cardiac renin-angiotensin system independently of hypertension in Dahl salt-sensitive rats?
High salt intake induces cardiac hypertrophy and increases cardiac ACE activity in Dahl salt-sensitive rats independently of blood pressure elevation.
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High salt may promote LV hypertrophy via ACE independently of BP; leaves open translation to human salt-sensitive hypertension.
Zhao et al. (2000) studied this question.
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