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April 1, 1990BloodOpen Access

Glanzmann's thrombasthenia: the spectrum of clinical disease

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Authors

JGJN GeorgeJCJP CaenANAT Nurden

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Overview

Clinical review demonstrates the phenotypic spectrum in 177 patients with Glanzmann thrombasthenia, highlighting variable disease severity.

Key Points

  • To characterize the clinical presentation, variability, and disease spectrum of Glanzmann's thrombasthenia in a large cohort of patients.
  • Retrospective review analyzing clinical data from a total of 177 patients with Glanzmann thrombasthenia.
  • Combined previously published data from 113 patients with clinical findings from 64 patients evaluated in Paris over a 33-year period.
  • Demonstrates significant clinical heterogeneity and a wide spectrum of bleeding manifestations across 177 cases of Glanzmann thrombasthenia.
  • Provides comprehensive longitudinal characterization based on 33 years of clinical follow-up in a single-center cohort of 64 patients.

Cite This Study

George et al. (1990) studied this question.

synapsesocial.com/papers/6a72c23c3ce530166bc3608dhttps://doi.org/10.1182/blood.v75.7.1383.bloodjournal7571383
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