What question did this study set out to answer?

To evaluate the acute and long-term clinical and echocardiographic outcomes of percutaneous mitral balloon valvuloplasty in patients with hemodynamically significant mitral stenosis.

August 11, 2011The Anatolian Journal of Cardiology

Acute and long-term follow-up results of percutaneous mitral balloon valvuloplasty: a single-center study

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Population

311 patients with hemodynamically significant mitral stenosis who underwent percutaneous mitral balloon…

Design

Cohort

Follow-up

at least 5 years (6.4±1.6 years for long-term subgroup)

Authors

ŞKŞule KorkmazBursa Uludağ Üni̇versi̇tesi̇BDBurcu DemirkanMemorial Ankara Hospital YGYeşım GürayTürkiye Yüksek İhtisas Hastanesi

Discussion

Member takes

Implication

≥60% acute MVA improvement was associated with fewer events after PMBV; hypothesis-generating and requires prospective validation before guiding practice.

Key Points

To evaluate the acute and long-term clinical and echocardiographic outcomes of percutaneous mitral balloon valvuloplasty in patients with hemodynamically significant mitral stenosis.
Retrospective cohort study evaluating 311 patients who underwent percutaneous mitral balloon valvuloplasty between January 2000 and March 2004 at a single tertiary center in Turkey.
All 311 patients were contacted at least 5 years post-procedure; 63 symptomatic patients (NYHA class II–IV) completed long-term echocardiographic follow-up for a mean of 6.4 ± 1.6 years.
Outcomes assessed included acute procedural success (mitral valve area ≥1.5 cm² without severe regurgitation) and primary composite endpoints (death, repeat valvuloplasty, or mitral valve replacement).
Acute procedural success was 94% across 311 patients and was independently associated only with preprocedural mitral valve area (Expβ = 0.004, 95% CI 0.0001–0.234, p = 0.008).
During long-term follow-up of 63 patients, those with an uneventful course had significantly higher immediate postprocedural mitral valve areas (p < 0.001) and lower mean (p = 0.001) and peak (p < 0.001) transmitral gradients.
Patients with at least 60% postprocedural improvement in mitral valve area experienced significantly fewer composite adverse endpoints than those with less than 60% improvement (5% vs. 30.4%, p = 0.009; Kaplan-Meier survival p = 0.003).

Structured PICO

Population

311 patients with hemodynamically significant mitral stenosis who underwent percutaneous mitral balloon valvuloplasty at a single center in Turkey

Intervention

Percutaneous mitral balloon valvuloplasty (PMBV)

Outcome

Acute procedural outcomes and primary endpoints (composite of death, rePMBV, mitral valve replacement (MVR))composite

Acute postprocedural mitral valve area improvement of at least 60% is significantly associated with better long-term event-free survival after percutaneous mitral balloon valvuloplasty.

Cite This Study

Korkmaz et al. (2011) studied this question.

synapsesocial.com/papers/6a72c2468031ec7bb1dd79b4 https://doi.org/10.5152/akd.2011.136

Topics

Echocardiography

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Implication

≥60% acute MVA improvement was associated with fewer events after PMBV; hypothesis-generating and requires prospective validation before guiding practice.

Acute and long-term follow-up results of percutaneous mitral balloon valvuloplasty: a single-center study

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Acute and long-term follow-up results of percutaneous mitral balloon valvuloplasty: a single-center study

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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