Why the study?
Does early or late perindopril therapy improve survival and myocardial contractility in cardiomyopathic Syrian hamsters?
Population
76 cardiomyopathic Syrian hamsters (CSH) from the Bio 53.58 dilated strain
Comparison
Perindopril 1 mg/kg body weight once daily in… vs Distilled water administered by force-feeding…
Design
Preclinical, Animals were randomly assigned to three groups
Follow-up
Up to 9 months of age
Authors
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Results unavailable; leaves open whether early or late perindopril affects survival or contractility in this hamster model.
Does early or late perindopril therapy improve survival and myocardial contractility in cardiomyopathic Syrian hamsters?
This preclinical study aimed to evaluate the effects of early versus late perindopril therapy on survival and myocardial contractility in a hamster model of dilated cardiomyopathy, though results are not available in the truncated abstract.
Chemla et al. (1994) studied this question.
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