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June 1, 1993The Pediatric Infectious Disease Journal

Infections Caused by Chlamydia Pneumoniae Strain Twar

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Authors

JGJ. Thomas GraystonStatens Serum Institut

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Implication

Clinical review demonstrates respiratory morbidity and vascular links of Chlamydia pneumoniae, highlighting an unexpected connection to atherosclerosis.

Key Points

  • To review the clinical characteristics, epidemiological patterns, and cardiovascular associations of respiratory infections caused by Chlamydia pneumoniae strain TWAR.
  • Reviewed clinical features and historical isolations of prototype strains TW-183 and AR-39.
  • Assessed seroepidemiological surveys and direct pathogen identification within human vascular atheromas.
  • Chlamydia pneumoniae primarily causes acute bronchitis and mild pneumonia with protracted recovery, with peak incidence and increased clinical severity occurring in elderly individuals.
  • Seroepidemiological findings and the direct physical detection of the organism within atheroma tissue correlate infection with atherosclerotic cardiovascular and coronary artery disease.

Cite This Study

J. Thomas Grayston (1993) studied this question.

synapsesocial.com/papers/6a72c27bf44fa9f079e020d9https://doi.org/10.1097/00006454-199306000-00028
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chlamydia pneumoniae sp. nov. for Chlamydia sp. Strain TWAR1989 · 380 citations
  2. 2Pneumonia with BALF Detection of Tropheryma whipplei and Chlamydia psittaci by Targeted Next-Generation Sequencing: A Case Report2026
  3. 3Severe pneumonia caused by Chlamydia psittaci and Aspergillus terreus: a case report2026
  4. 4Demonstration of Chlamydia pneumoniae in Atherosclerotic Lesions of Coronary Arteries1993 · 768 citations
  5. 5Community‐Acquired <i>Chlamydia psittaci</i> Severe Pneumonia: A Case Report2025 · 1 citations