Why the study?
Does measurement of serum cTnI and CK-MB help diagnose cardiac muscle cell injury in patients with clinically suspected myocarditis?
Does measurement of serum cTnI and CK-MB help diagnose cardiac muscle cell injury in patients with clinically suspected myocarditis?
Elevated cTnI can serve as a useful indicator of cardiac muscle cell injury in patients with clinically suspected myocarditis, particularly when endomyocardial biopsy is not feasible.
Cardiac troponin I may aid myocarditis diagnosis where biopsy is unavailable; leaves open validation in prospective cohorts.
BACKGROUND methods used to diagnose or rule out myocarditis is not useful in detecting cardiac myocyte injury in clinically cases. Endomyocardial biopsy and histopathological examination is not feasible in most government hospitals in . Sensitive parameters have yet to be found out. The study was conducted to find out whether diagnosis of myocarditis clinically suspected cases can be done by measurement of serum levels of cardiac troponinI (cTnI) and MB isoform of kinase (CK-MB). AND METHODS 19 patients with clinically suspected myocarditis were screened for CK-MB activity and cTnI. Echocardiography, ECG and IgM leptospirosis were also checked in these patients. was elevated in 10 out of 19 patients with clinically suspected myocarditis. CK-MB was elevated in 7 patients. of cTnI level in blood can be taken as an indicator of cardiac muscle cell injury in suspected cases of myocarditis.
No takes yet. Share an insight, caveat, or question.
Bharathan et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: