Why the study?
Do non-invasive diagnostic methods (MRI and autoantibodies) provide sufficient diagnostic sensitivity for myocarditis compared to endomyocardial biopsy in patients with suspected myocarditis?
Do non-invasive diagnostic methods (MRI and autoantibodies) provide sufficient diagnostic sensitivity for myocarditis compared to endomyocardial biopsy in patients with suspected myocarditis?
Cardiac MRI has high sensitivity for acute myocarditis, but its lower sensitivity in chronic cases confirms the ongoing necessity of endomyocardial biopsy for definitive diagnosis in chronic inflammation.
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MRI sensitivity of 67% warrants caution against sole reliance on noninvasive diagnosis; leaves open the need for biopsy confirmation in chronic myocarditis.
Титов et al. (2018) studied this question.
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