Population
Skeletal myosin motor domain (S-1)
Design
Preclinical
Authors
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No immediate clinical implications; leaves open translation of myosin states to cardiac function in vivo.
Fluorescence spectroscopy of labeled skeletal myosin reveals distinct structural states during actin and nucleotide binding, providing insight into the allosteric linkage between the ATPase site and the actin binding site.
Bertrand et al. (2000) studied this question.
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