Why the study?
The study was conducted to analyze the relationship between 1-year outcomes and respiratory comorbidity in patients with CAD undergoing scheduled CABG, and to determine predictors of fatal outcomes.
Does comorbid respiratory disease worsen 1-year cardiovascular outcomes in patients with coronary artery disease undergoing scheduled CABG?
Does comorbid respiratory disease worsen 1-year cardiovascular outcomes in patients with coronary artery disease undergoing scheduled CABG?
COPD, along with incomplete revascularization and reduced LVEF, is a significant predictor of poor 1-year outcomes in patients undergoing scheduled CABG.
Respiratory comorbidity may affect 1-year post-CABG outcomes; hypothesis-generating and leaves open need for confirmation in prospective studies.
The first goal of this study was to analyze a relationship between 1-year outcomes and respiratory comorbidity in patients with coronary artery disease (CAD) underwent scheduled coronary artery bypass grafting (CABG); the second goal of the study was to determine the most significant predictors of fatal outcome in these patients. Methods. The study involved 251 patients underwent CABG. They were stratified according to having comorbid chronic obstructive (n = 62; 24.7%) or non-obstructive lung disease (n = 65; 25.9%) or not having chronic respiratory disease (n = 124; 49.4%). Cardiovascular events during 1 year were registered. Results. An expected decrease in functional classes of CAD and chronic heart failure (CHF) was noted over 1 year. Number of non-fatal significant cardiovascular events didn’t differ in patients with or without chronic obstructive pulmonary disease (COPD). Seven patients (2.78%) died during the year; the cause of death was cardiovascular disease in all cases. Factors predicting poor outcomes included age, occupational exposure to chemicals > 3 years, incomplete myocardial revascularization, FEV1/FVC ratio, and left ventricular ejection fraction < 40%. Conclusion. COPD is a predictor of poor outcome of myocardial revascularization in patients with CAD.
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Баздырев et al. (2019) studied this question.
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