Key result
Preoperative FEV1 <60% in patients undergoing coronary artery bypass grafting was associated with significantly higher in-hospital mortality compared to FEV1 >60% (24.6% vs 1.4%; p<0.001).
Why the study?
Does severe chronic obstructive pulmonary disease (FEV1 <60%) increase in-hospital mortality in patients undergoing CABG?
Population
1,412 patients undergoing coronary artery bypass grafting from May 1993 to December 2004 with preoperative…
Comparison
Severe chronic obstructive pulmonary disease vs Normal pulmonary function or mild/moderate disease
Design
Cohort
Follow-up
in-hospital
Authors
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Supports FEV1 inclusion in CABG risk models; leaves open whether thresholds should alter decisions or require prospective validation.
Cohort (n=1,412)
Does severe chronic obstructive pulmonary disease (FEV1 <60%) increase in-hospital mortality in patients undergoing CABG?
Absolute Event Rate: 24.6% vs 1.4%
p-value: p=<0.001
Preoperative FEV1 <60% is a strong prognostic factor for in-hospital mortality in patients undergoing CABG and should be considered in operative risk assessment.
Fúster et al. (2005) conducted a cohort in Coronary artery bypass grafting (n=1,412). Preoperative FEV1 < 60% vs. Preoperative FEV1 > 60% was evaluated on In-hospital mortality (p=<0.001). Preoperative FEV1 <60% in patients undergoing coronary artery bypass grafting was associated with significantly higher in-hospital mortality compared to FEV1 >60% (24.6% vs 1.4%; p<0.001).
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