July 1, 1990Pacing and Clinical Electrophysiology
Magnesium Therapy in Ventricular Arrhythmias
Why the study?
Does magnesium therapy reduce ventricular arrhythmias and improve survival in patients with digitalis toxicity, torsade de pointes, diuretic therapy, or acute myocardial infarction?
Population
Patients with digitalis toxicity, drug-induced torsade de pointes, chronic diuretic therapy, or acute…
Design
Review
Authors
Discussion
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Implication
May support magnesium in digitalis toxicity and torsades; leaves open randomized confirmation of survival benefit in acute MI.
Structured PICO
Does magnesium therapy reduce ventricular arrhythmias and improve survival in patients with digitalis toxicity, torsade de pointes, diuretic therapy, or acute myocardial infarction?
P
Population
Patients with digitalis toxicity, drug-induced torsade de pointes, chronic diuretic therapy (hypertensives), or acute myocardial infarction
I
Intervention
Magnesium therapy (e.g., magnesium sulfate)
O
Outcome
Ventricular tachyarrhythmias and survival
Magnesium is an effective first-line therapy for digitalis intoxication and drug-related torsade de pointes, and an important adjuvant in diuretic-treated hypertensives and acute myocardial infarction.
Cite This Study
Keren et al. (1990) studied this question.