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October 1, 2005Pacing and Clinical Electrophysiology

Chronotropic Incompetence in Patients with an Implantable Cardioverter Defibrillator: Prevalence and Predicting Factors

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Population

123 patients with an implantable cardioverter defibrillator, including those with single-chamber ICD with…

Design

Cross-sectional

Authors

CMChristoph MelzerMBM BöhmHBHANS JOACHIM BONDKE

Discussion

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Overview

Chronotropic incompetence links to reduced exercise capacity in ICD patients; cross-sectional data leave open whether rate-adaptive pacing improves outcomes.

Structured PICO

P
Population
123 patients with an implantable cardioverter defibrillator (ICD), including those with single-chamber ICD with sinus rhythm, dual-chamber ICD with sinus rhythm, and single-chamber ICD with permanent atrial fibrillation.
O
Outcome
Prevalence of chronotropic incompetence and its predicting factorssurrogate

A significant proportion (38%) of ICD patients exhibit chronotropic incompetence, which is associated with reduced exercise capacity and may warrant optimized rate-adaptive pacing strategies.

Cite This Study

Melzer et al. (2005) studied this question.

synapsesocial.com/papers/6a72c35efe4101aa97e0ef20https://doi.org/10.1111/j.1540-8159.2005.00239.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chronotropic Response to Exercise in Patients with Atrial Fibrillation1990 · 58 citations
  2. 2Aerobic Capacity in Rate Modulated Pacing1992 · 25 citations
  3. 3Respiratory‐Dependent Atrial Pacing, Management of Sinus Node Disease1988 · 22 citations
  4. 4Atrial adaptive rate pacing in sick sinus syndrome: effects on exercise capacity and arrhythmias.1993 · 27 citations
  5. 5The Role of Pacing Modality in Determining Long-Term Survival in the Sick Sinus Syndrome1993 · 57 citations