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February 1, 2005Blood Pressure Monitoring

Diurnal variation of blood pressure; reproducibility and association with left ventricular hypertrophy in hemodialysis patients

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Why the study?

Does a non-dipping pattern of diurnal blood pressure associate with increased left ventricular mass index in hemodialysis patients?

Population

59 hemodialysis patients, 88% African-American

Comparison

Non-dipping pattern of diurnal blood pressure vs Dipping pattern of diurnal blood pressure

Design

Cross-sectional

Follow-up

6 and 12 months (for reproducibility subset)

Authors

MRMahboob RahmanPreventive CardiologyVGV GriffinSouthern Illinois University EdwardsvilleRHRobert HeykaCleveland Clinic

Discussion

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Implication

Non-dipping nocturnal BP was associated with higher LVMI in HD patients; hypothesis-generating and requires prospective confirmation before clinical adoption.

Structured PICO

Does a non-dipping pattern of diurnal blood pressure associate with increased left ventricular mass index in hemodialysis patients?

P
Population
59 hemodialysis patients, 88% African-American
I
Intervention
Non-dipping pattern of diurnal blood pressure (night/day systolic and diastolic BP ratio >0.9 on both days of 44-h ABPM)
C
Comparator
Dipping pattern of diurnal blood pressure
O
Outcome
Left ventricular mass index (LVMI) measured by echocardiographysurrogate

In hemodialysis patients, a non-dipping nocturnal blood pressure profile is highly reproducible and independently associated with increased left ventricular mass index.

Cite This Study

Rahman et al. (2005) studied this question.

synapsesocial.com/papers/6a72c578a528af2d65c4893ahttps://doi.org/10.1097/00126097-200502000-00006

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Limited Reproducibility of Circadian Variation in Blood Pressure Dippers and Nondippers1998 · 165 citations
  2. 2Left ventricular hypertrophy and nocturnal hypoxemia in hemodialysis patients2001 · 64 citations
  3. 3Hypertension is Not Adequately Controlled in Hemodialysis Patients1992 · 184 citations
  4. 4Validation of the SpaceLabs 90207 ambulatory blood pressure device for hemodialysis patients1999 · 31 citations
  5. 5Editorials: Assessment of Blood Pressure in Hemodialysis Patients2002 · 47 citations