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This research aims to compare the stability of alginate and agarose hydrogels over a 90-day period, focusing on gel strength and protein diffusion.

Stability of hydrogels used in cell encapsulation: An in vitro comparison of alginate and agarose

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This research aims to compare the stability of alginate and agarose hydrogels over a 90-day period, focusing on gel strength and protein diffusion.
Evaluated gel strength of alginate and agarose over 90 days
Monitored protein diffusion in calcium-crosslinked sodium alginate over 60 days
Estimated pore size increase in alginate gels using a semi-empirical model.
Agarose gel strength decreased by 25% in the presence of cells within 60 days, stabilizing thereafter.
Calcium and barium-crosslinked alginate gel strengths were similar after 60 days at 350 +/- 20 g and 300 +/- 60 g, respectively.
Pore size of calcium-crosslinked alginate gels increased from approximately 176 to 289 A over 60 days.

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Randomized trial evaluates gel stability and protein diffusion in alginate and agarose hydrogels, suggesting differences in stability over time.

Shoichet et al. (1996) studied this question.

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Randomized trial evaluates gel stability and protein diffusion in alginate and agarose hydrogels, suggesting differences in stability over time.