Why the study?
Does antegrade perfusion reduce hospital mortality and neurologic complications compared to deep hypothermia in newborns undergoing aortic arch reconstruction?
Does antegrade perfusion reduce hospital mortality and neurologic complications compared to deep hypothermia in newborns undergoing aortic arch reconstruction?
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Antegrade perfusion during aortic arch reconstruction in newborns may reduce hospital mortality and neurologic complications compared to deep hypothermia, but is associated with a high rate of renal complications.
Results of surgical treatment in 31 patients with different congenital aortic arch pathologies are presented. Two intraoperative methods of cerebral protection: deep hypothermia (n = 15), antegrade perfusion (n = 16) were used over a period from 2008 to 2012. Hospital mortality and neurologic complications in the antegrade perfusion group were significantly lower than those in the deep hypothermia group. However, a high rate of renal complications requires further investigation of this problem, identification of possible causes and improvement of the method.
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Sinelnikov et al. (2015) studied this question.
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