Can mRNA vaccine against COVID-19 cause pancytopenia?

COVID-19 pandemic changed the world. The fight against acquiring this virus went from social distancing, lockdowns and wearing masks, to mass vaccinations. Several vaccines invaded the market, and nations raced towards vaccinating all the population in order to reach herald immunity. mRNA vaccine is one of the most commonly used vaccine nowadays, and although it has a very high efficacy rate, many side effects were reported. A previously healthy young woman presented to our hospital, 1 week after receiving her first COVID-19 mRNA vaccine due severe aphthous ulcers, fatigue and fever. The patient was found to have pancytopenia. Although several side effects were reported to all the COVID-19 vaccines, pancytopenia is not one of the most commonly reported side effects in the literature. In this case report, we talk about is mentioned in the literature, the clinical picture of this patient, the evolution during her hospitalization, and the outcome.