Why the study?
Does intravenous erythromycin cause QT prolongation and torsades de pointes in patients without significant heart disease?
Does intravenous erythromycin cause QT prolongation and torsades de pointes in patients without significant heart disease?
Intravenous erythromycin can induce QT prolongation and torsades de pointes even in patients without underlying heart disease or other predisposing factors.
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May warrant QT monitoring with IV erythromycin even without heart disease; hypothesis-generating case report leaves open broader confirmation.
Brandriss et al. (1994) studied this question.
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