The study successfully validates a 3-D fluid-structure interaction numerical model of a prosthetic aortic valve against experimental measurements, providing a promising computational tool for investigating clinical issues.
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Validated 3-D FSI model supports in silico valve studies; leaves open clinical translation pending human data.
A numerical 3-D fluid-structure interaction (FSI) model of a prosthetic aortic valve was developed, based on a commercial computational fluid dynamics (CFD) software program using an Arbitrary Eulerian Lagrangian (ALE) formulation. To make sure of the validity of this numerical model, an equivalent experimental model accounting for both the geometrical features and the hydrodynamic conditions was also developed. The leaflet and the flow behaviours around the bileaflet valve were investigated numerically and experimentally by performing particle image velocimetry (PIV) measurements. Through quantitative and qualitative comparisons, it was shown that the leaflet behaviour and the velocity fields were similar in both models. The present study allows the validation of a fully coupled 3-D FSI numerical model. The promising numerical tool could be therefore used to investigate clinical issues involving the aortic valve.
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Guivier‐Curien et al. (2009) studied this question.
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