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April 1, 2023Nigerian Journal of Clinical PracticeOpen Access

Clinical Predictors of Covid-19 Mortality in a Tertiary Hospital in Lagos, Nigeria: A Retrospective Cohort Study

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Authors

IAIorhen E. AkasePAPE AkintanEOErere Otrofanowei

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Overview

Retrospective cohort study reveals that age over 50 and chronic comorbidities increase COVID-19 mortality in hospitalized individuals, highlighting the need for targeted intensive care resources.

Key Points

  • To identify clinical predictors of mortality among COVID-19 patients admitted to a tertiary referral hospital in Lagos, Nigeria.
  • Conducted a retrospective cohort study of N=734 patients admitted with COVID-19 at a single tertiary hospital.
  • Documented sociodemographics, clinical characteristics, medical comorbidities, complications, and hospital duration.
  • Evaluated predictors of survival using Kaplan-Meier curves, log-rank tests, and multivariable Cox proportional hazards analysis.
  • The overall hospital mortality rate was 9.07 per 1,000 person-days among the 734 admitted patients (mean age 47.4 ± 17.2 years; 58.5% male).
  • Deceased patients had a higher prevalence of one or more comorbidities compared to discharged patients (73.9% [51/69] vs. 41.6% [252/606]).
  • Mortality showed a statistically significant relationship with age over 50 years, diabetes mellitus, hypertension, chronic renal illness, and cancer.

Cite This Study

Akase et al. (2023) studied this question.

synapsesocial.com/papers/6a72ceb15d37378ac1df6e73https://doi.org/10.4103/njcp.njcp_454_22
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