September 1, 1997Biochemistry

X-ray Structures of the MgADP, MgATPγS, and MgAMPPNP Complexes of the Dictyostelium discoideum Myosin Motor Domain,

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Population

Truncated myosin head from Dictyostelium discoideum myosin II (S1dC)

Design

Preclinical

Authors

AGAndrew M. GulickJacobs (United States)CBCary B. BauerBruker (United States)JTJames B. ThodenUniversity of Wisconsin–Madison

Discussion

Member takes

Implication

Identifies prehydrolysis weak binding myosin state; leaves open relevance to human cardiac contractility.

Structured PICO

Population

Truncated myosin head from Dictyostelium discoideum myosin II (S1dC)

Intervention

Complexation with MgAMPPNP, MgATPgammaS, and MgADP

Outcome

Three-dimensional structures at 2.1, 1.9, and 2.1 A resolutionsurrogate

The structural analysis of Dictyostelium discoideum myosin II complexes reveals that the conformation observed represents the prehydrolysis weak binding state of myosin.

Cite This Study

Gulick et al. (1997) studied this question.

synapsesocial.com/papers/6a72cecb3760af5e893dad48 https://doi.org/10.1021/bi9712596

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X-ray Structures of the MgADP, MgATPγS, and MgAMPPNP Complexes of the Dictyostelium discoideum Myosin Motor Domain,

Discussion

Member takes

Implication

Structured PICO

Cite This Study

X-ray Structures of the MgADP, MgATPγS, and MgAMPPNP Complexes of the Dictyostelium discoideum Myosin Motor Domain,

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider