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July 21, 1949New England Journal of Medicine

Infarction of the Interventricular Septum

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Why the study?

What are the electrocardiographic findings associated with infarction of the interventricular septum?

Population

Patients with infarction of the interventricular septum at the Veterans Administration Hospital in West…

Design

Case_series

Authors

DLDavid LittmannTufts University

Discussion

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Implication

Facilitates ECG recognition of septal infarction; leaves open validation against modern imaging and outcomes.

Key Points

  • To evaluate the electrocardiographic and pathological features associated with extensive infarction of the interventricular septum involving adjacent ventricular walls.
  • Conducted a retrospective review of clinical and pathological records from a Veterans Administration hospital over a 27-month period (May 1946 to August 1948).
  • Correlated standard limb leads and precordial electrocardiographic tracings with post-mortem pathological findings.
  • Extensive infarction involving the interventricular septum and segments of both anterior and posterior walls produced a characteristic dual electrocardiographic pattern.
  • Tracings consistently demonstrated posterior myocardial infarction signs in standard limb leads alongside anteroseptal infarction signs across precordial leads.

Structured PICO

What are the electrocardiographic findings associated with infarction of the interventricular septum?

P
Population
Patients with infarction of the interventricular septum at the Veterans Administration Hospital in West Roxbury, Massachusetts
O
Outcome
Electrocardiographic findingssurrogate

The study reviews clinical and pathological material to characterize the electrocardiographic patterns of extensive interventricular septal infarction.

Cite This Study

David Littmann (1949) studied this question.

synapsesocial.com/papers/6a72d3efb0d581bd9f303bachttps://doi.org/10.1056/nejm194907212410302
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The QRS complex of the standard 12-lead electrocardiogram in septal myocardial infarction.1988 · 7 citations
  2. 2Rupture of the Interventricular Septum1950 · 21 citations
  3. 3Perforation of Infarcted Interventricular Septum1962 · 96 citations
  4. 4PERFORATION OF THE INTERVENTRICULAR SEPTUM1952 · 25 citations
  5. 5RUPTURE OF THE INTERVENTRICULAR SEPTUM DUE TO MYOCARDIAL INFARCTION: REPORT OF TWO CASES1954 · 4 citations