Why the study?
Does a family history of hypertension affect echocardiographic parameters in normotensive children?
Does a family history of hypertension affect echocardiographic parameters in normotensive children?
Normotensive children with a family history of hypertension exhibit subtle echocardiographic changes, such as a higher interventricular septum/posterior wall ratio, which may indicate early subclinical cardiac remodeling.
May indicate early subclinical remodeling in normotensive offspring; leaves open whether family history predicts future cardiac risk.
A family history of hypertension is considered a risk factor for developing hypertension. We studied two groups of normotensive children (aged 14 years): one comprising 14 subjects with family history of hypertension, the other comprising 15 subjects without family history of hypertension. Children were comparable with respect to age, weight, height, body surface area, heart rate, and arterial blood pressure. M-mode echocardiography demonstrated higher interventricular septum/posterior wall ratio in progeny of hypertensive subjects. Interestingly, all the parameters evaluated were within the normal limits. Our data suggest that a certain degree of cardiac changes is present in children with positive family history of hypertension, though further studies are needed before considering these findings predictive of future essential hypertension.
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Leonardos et al. (1988) studied this question.
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