Population
Expressed full-length myosin V (dFull) and three shorter constructs
Comparison
Calcium and calmodulin (CaM) vs EGTA (calcium-free conditions)
Design
Preclinical
Authors
Loading...
Calcium-dependent myosin V regulation may affect cellular transport; leaves open extension to mammalian systems or therapeutic relevance.
Myosin V transport ability is regulated by a folded-to-extended conformational change controlled by calcium, calmodulin, and likely cargo binding.
Krementsov et al. (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: