A combination therapy to treat second-degree anti-Ro/La-related congenital heart block. A strategy to avoid stable third-degree heart block?

2 cases of anti-Ro/La-related second-degree congenital heart block

Betamethasone (4 mg/day), weekly plasmapheresis, and intravenous immunoglobulins (IVIGs; 1 g/kg) administered every 15 days from shortly after detection until delivery, followed by newborn treatment with IVIG (1 g/kg) fortnightly until anti-Ro/La antibody levels became undetectable

Reversion of second-degree AV block to stable sinus rhythm with first-degree AV blocksurrogate