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December 19, 2023Open Access

Patients with an indexed left atrial epicardial adipose tissue (EATi) <10.65% showed significantly greater survival free from arrhythmias compared to those with values above this cut-off (84% vs. 48%; p=0.04).

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Why the study?

Previous literature on epicardial adipose tissue and AF showed great heterogeneity and focused primarily on CT imaging, leaving unclear whether LA EAT volume on pre-procedural cardiac MRI relates to AF recurrence after ablation.

Does left atrial epicardial adipose tissue volume evaluated by cardiac MRI predict atrial fibrillation recurrence after cryoballoon ablation?

Population

50 patients undergoing AF cryoballoon ablation and pre-procedural cardiac MRI

Comparison

Higher vs lower left atrial epicardial adipose tissue volume

Design

Cohort study

Follow-up

Median 16.0 months

Authors

ABAndrea BallatoreMGMarco GattiSMSerena Mella

Discussion

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Member takes

Overview

LA EAT volume on pre-procedural MRI may flag higher post-ablation recurrence risk; leaves open incremental value beyond clinical predictors.

Structured PICO

Does left atrial epicardial adipose tissue volume evaluated by cardiac MRI predict atrial fibrillation recurrence after cryoballoon ablation?

P
Population
50 patients undergoing atrial fibrillation (AF) cryoballoon ablation and pre-procedural cardiac MRI allowing quantification of left atrial epicardial adipose tissue (LA EAT).
I
Intervention
Quantification of left atrial epicardial adipose tissue (LA EAT) volume indexed to the left atrium (EATi) using pre-procedural cardiac MRI
O
Outcome
Atrial fibrillation (AF) recurrence after catheter ablationhard clinical

Indexed left atrial epicardial adipose tissue volume measured by pre-procedural cardiac MRI may help predict atrial fibrillation recurrence following cryoballoon ablation.

Cite This Study

Ballatore et al. (2023) studied this question.

synapsesocial.com/papers/6a72e54dc94dd74093748727https://doi.org/10.20944/preprints202312.1440.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epicardial Atrial Fat at Cardiac Magnetic Resonance Imaging and AF Recurrence after Transcatheter Ablation2024 · 3 citations
  2. 2MRI-quantified left atrial epicardial adipose tissue predicts atrial fibrillation recurrence following catheter ablation2022 · 13 citations
  3. 3The Relationship between Enhancing Left Atrial Adipose Tissue at CT and Recurrent Atrial Fibrillation2022 · 39 citations
  4. 4Association Between Epicardial Adipose Tissue Volumes on 3-Dimensional Reconstructed CT Images and Recurrence of Atrial Fibrillation After Catheter Ablation2011 · 140 citations
  5. 5Predictive Value of Epicardial Adipose Tissue Parameters Measured by Cardiac Computed Tomography for Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation2025 · 2 citations