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December 21, 2022International Journal of Drug Discovery and PharmacologyOpen Access

Cardiac β-Adrenoceptor Signaling: The New Insight on An Old Target in the Therapy of Cardiovascular Disease

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Why the study?

To provide an overview of recent progress in basic research of G protein-coupled receptors with a focus on cardiac beta-adrenoceptor signal transduction.

Design

Review

Authors

YSYing SongAWAnthony Yiu‐Ho WooYZYan Zhang

Discussion

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Overview

New insights on β-adrenoceptor signaling may refine targeting in heart failure; leaves open prospective validation before practice change.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Song et al. (2022) studied this question.

synapsesocial.com/papers/6a72e7198ca63dee9860d690https://doi.org/10.53941/ijddp.v1i1.177
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Targeting β3-Adrenergic Receptors in the Heart: Selective Agonism and β-Blockade2016 · 92 citations
  2. 2Cardiac Adrenoceptors: Physiological and Pathophysiological Relevance2006 · 242 citations
  3. 3β-Adrenergic Signaling in the Heart: Dual Coupling of the β <sub>2</sub> -Adrenergic Receptor to G <sub>s</sub> and G <sub>i</sub> Proteins2001 · 263 citations
  4. 4Biased β<sub>2</sub>‐adrenoceptor signalling in heart failure: pathophysiology and drug discovery2014 · 74 citations
  5. 5Beta-adrenoceptor signaling pathways mediate cardiac pathological remodeling2011 · 33 citations