What question did this study set out to answer?

To compare the effectiveness of NICE criteria and BOADICEA model in assessing breast cancer risk in women under 50.

August 5, 2026British Journal of CancerOpen Access

Comparison of NICE criteria with the BOADICEA multifactorial risk model to guide breast cancer risk assessment and referral amongst women under age 50 within primary care

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To compare the effectiveness of NICE criteria and BOADICEA model in assessing breast cancer risk in women under 50.
Analyzed data from 1258 women under 50 participating in the Generations Study.
Assessed performance of NICE criteria and BOADICEA model in identifying women who developed breast cancer within 10 years.
Considered factors such as family history, reproductive data, lifestyle, and polygenic risk.
NICE criteria identified 4.4% of women who developed breast cancer within 10 years.
Full BOADICEA model identified up to 35% of women with lower specificity.
26.5% of women met the referral criteria according to the BOADICEA model.

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Implication

Randomized trial compares NICE criteria with BOADICEA model for breast cancer risk in women under 50, suggesting improved identification and management.

Cite This Study

Frost et al. (2026) studied this question.

synapsesocial.com/papers/6a72e79c226790f370656cab https://doi.org/10.1038/s41416-026-03547-2

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Implication

Randomized trial compares NICE criteria with BOADICEA model for breast cancer risk in women under 50, suggesting improved identification and management.

Comparison of NICE criteria with the BOADICEA multifactorial risk model to guide breast cancer risk assessment and referral amongst women under age 50 within primary care

Key Points

Discussion

Implication

Cite This Study

Comparison of NICE criteria with the BOADICEA multifactorial risk model to guide breast cancer risk assessment and referral amongst women under age 50 within primary care

Key Points

Discussion

Implication

Cite This Study

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