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August 5, 2026International Journal of Adhesion and AdhesivesOpen Access

Development and characterization of Pelargonium graveolens extract-loaded carrageenan/polyethylene glycol composite films for bioactive wound dressing applications

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Authors

HEHany M. Abd El‐LateefMKMai M. KhalafMAMahmoud A. Abdelaziz

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Overview

Study develops bioactive wound dressings using Pelargonium graveolens extract in composite films, indicating promising applications.

Key Points

  • The study aims to develop and characterize composite films incorporating Pelargonium graveolens extract for wound dressing applications.
  • Prepared bioactive films using different concentrations of Pelargonium graveolens extract in carrageenan/polyethylene glycol composites
  • Conducted HPLC analysis for compound identification, including phenolic and flavonoid contents
  • Evaluated antioxidant, antibacterial activities, and fibroblast scratch closure in vitro.
  • PGE-4@CAR/PEG showed the highest total phenolic (34.4 mg GAE/g) and flavonoid (14.7 mg QE/g) contents
  • PGE-4@CAR/PEG increased fibroblast scratch closure from 63.50 ± 0.70% to 67.14 ± 0.64% (p = 0.0027) after 48 hours
  • PGE exhibited significant antioxidant activity with IC 50 values of 79.47 μg/mL (DPPH) and 91.27 μg/mL (ABTS).

Cite This Study

El‐Lateef et al. (2026) studied this question.

synapsesocial.com/papers/6a72e79c226790f370656dabhttps://doi.org/10.1016/j.ijadhadh.2026.104423
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