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August 5, 2026The Journal of Maternal-Fetal & Neonatal MedicineOpen Access

Comparative study of endostatin levels in preeclampsia pregnancy and normal pregnancy

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Authors

CPChatprateep PoosawangChulalongkorn UniversityVPVorapong PhupongChulalongkorn University

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Implication

Cross-sectional analysis compares endostatin levels in preeclampsia and normal pregnancies, indicating potential implications for monitoring maternal health.

Key Points

  • The study aimed to compare endostatin levels in preeclampsia with those in normal pregnancies and analyze maternal and neonatal outcomes.
  • Cross-sectional analytic study with 68 preeclampsia and 68 normal pregnancies matched for gestational age.
  • Blood samples were collected and endostatin levels were measured using enzyme-linked immunosorbent assays (ELISA).
  • Maternal and neonatal outcomes were recorded and analyzed.
  • No significant difference in median serum endostatin levels between preeclampsia (3.45 ng/ml) and normal pregnancies (4.32 ng/ml), p=0.304.
  • Higher cesarean delivery rate in preeclampsia (63.2%) compared to normal pregnancies (41.2%), p=0.01.
  • Preeclampsia patients had lower neonatal birth weight (2,419 g) and longer hospital stays (median 5 days) compared to normal pregnancies (2,903 g and 4 days, p<0.001).

Cite This Study

Poosawang et al. (2026) studied this question.

synapsesocial.com/papers/6a72e79c226790f370656e13https://doi.org/10.1080/14767058.2026.2702813
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