Why the study?
Are maternal plasma endothelin-1 (ET-1) levels associated with clinical parameters in preeclampsia?
Are maternal plasma endothelin-1 (ET-1) levels associated with clinical parameters in preeclampsia?
Plasma endothelin-1 levels are elevated in preeclampsia and correlate with the severity of hypertensive disorders in pregnancy, suggesting a role in its pathophysiology.
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ET-1 elevation may mark preeclampsia severity; hypothesis-generating for causal role and targeted therapies.
Pouta et al. (1998) studied this question.
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