What question did this study set out to answer?

To explore how changes in D-dimer levels relate to localized coagulation after surgery in venous malformations.

August 5, 2026Annals of MedicineOpen Access

Association between perioperative D-dimer dynamics and post-treatment localized intravascular coagulation in venous malformations

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Authors

RZRong ZhangFuzhou Maternity and Child Health Care Hospital HLHuiming LuoCounty Hospital LJLiuyan JiangFujian Medical University

Discussion

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Implication

Retrospective cohort study investigates D-dimer change and post-surgical localized coagulation in venous malformations, suggesting potential risk marker implications.

Key Points

To explore how changes in D-dimer levels relate to localized coagulation after surgery in venous malformations.
Retrospective cohort study of 267 patients with venous malformations undergoing surgery.
Primary exposure was the change in D-dimer levels from preoperative to postoperative periods.
Used multivariable logistic regression to adjust for confounders.
ΔD-dimer is independently linked to postoperative localized intravascular coagulation (LIC).
Suggested threshold for ΔD-dimer near 4.8 mg/L FEU for monitoring risk of LIC, needing further validation.
Findings were consistent across various subgroups with no substantial interactions.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a72e7d2226790f3706571aa https://doi.org/10.1080/07853890.2026.2711537

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August 5, 2026Annals of MedicineOpen Access

Association between perioperative D-dimer dynamics and post-treatment localized intravascular coagulation in venous malformations

View Full Paper

Ask AI

Bookmark

Authors

RZRong ZhangFuzhou Maternity and Child Health Care Hospital HLHuiming LuoCounty Hospital LJLiuyan JiangFujian Medical University

Discussion

Member takes

Implication

Retrospective cohort study investigates D-dimer change and post-surgical localized coagulation in venous malformations, suggesting potential risk marker implications.

Key Points

To explore how changes in D-dimer levels relate to localized coagulation after surgery in venous malformations.
Retrospective cohort study of 267 patients with venous malformations undergoing surgery.
Primary exposure was the change in D-dimer levels from preoperative to postoperative periods.
Used multivariable logistic regression to adjust for confounders.
ΔD-dimer is independently linked to postoperative localized intravascular coagulation (LIC).
Suggested threshold for ΔD-dimer near 4.8 mg/L FEU for monitoring risk of LIC, needing further validation.
Findings were consistent across various subgroups with no substantial interactions.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a72e7d2226790f3706571aa https://doi.org/10.1080/07853890.2026.2711537

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