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August 5, 2026npj Biomedical Innovations.Open Access

High-channel-count neural recording and stimulation platform with 5376 simultaneous recording channels

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Authors

YFYingying FanWuyi UniversityYMYuhang MaRice UniversityPZPavlo ZolotavinRice University

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Overview

Randomized trial demonstrates high-resolution neural mapping in rat brains, suggesting advancements in interface technology.

Key Points

  • This research aims to develop a scalable neural recording platform with high-density channels for effective signal acquisition across brain regions.
  • Custom-designed ASIC with 5376 recording channels sampling at 20 kS/s
  • Integration of flexible μECoG array with ASIC
  • Gold bump bonding for high-density integration
  • Achieved a total data streaming throughput of >1.3 Gb/s
  • Maintained a low noise level of 5.5 µVrms during signal acquisition
  • Enabled precise localization of evoked sensory activities in vivo

Cite This Study

Fan et al. (2026) studied this question.

synapsesocial.com/papers/6a72e85b226790f3706583cdhttps://doi.org/10.1038/s44385-026-00103-8
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